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- Bioss
- bs-21328R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-21328R-AP |
| 英文名称 | Syndecan 4 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的 多配体聚糖4抗体 |
| 英文别名 | Amphiglycan; Amphiglycan; MGC22217; OTTHUMP00000031788; ryudocan amphiglycan; Ryudocan; Ryudocan core protein; Ryudocan core protein; SDC 4; SDC4; SDC4_HUMAN; SYND 4; SYND4; syndecan 4; syndecan 4(amphiglycan, ryudocan); syndecan proteoglycan 4; Syndecan-4; Syndecan4. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Syndecan 4 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Homodimer. Interacts (via its cytoplasmic domain) with GIPC (via its PDZ domain). Interacts (via its cytoplasmic domain) with NUDT16L1. Interacts with CDCP1 and SDCBP. |
| 亚细胞定位 | Isoform 1: Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form. Isoform 2: Secreted. |
| 组织特异性 | Expressed in epithelial and fibroblastic cells. |
| 翻译后修饰 | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| 相似性 | Belongs to the syndecan proteoglycan family. |
| 功能 | Cell surface proteoglycan that bears heparan sulfate. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly. Syndecan-4 is a transmembrane protein specifically enriched in Schwann cell perinodal processes. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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Syndecan 4 Rabbit pAb, AP conjugated(bs-21328R-AP)-100ul
￥2980
