Adenosine deaminase Rabbit pAb, HRP conjugated(bs-6654R-HRP)-100ul

Adenosine deaminase Rabbit pAb

, HRP conjugated(bs-6654R-HRP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-6654R-HRP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-6654R-HRP
    英文名称Adenosine deaminase Rabbit pAb, HRP conjugated
    中文名称HRP标记的腺苷脱氨酶(ADA)抗体
    英文别名ADA; ADA1; ADA_HUMAN; Adenosine aminohydrolase;
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Adenosine deaminase
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Response to hypoxia

    Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Deamination

    Metabolism > Pathways and Processes > Metabolism processes > Hypoxia

    Metabolism > Types of disease > Cancer

    亚基Interacts with DPP4 (extracellular domain).
    亚细胞定位Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm.
    组织特异性Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues.
    翻译后修饰The Ser/Thr-rich domain is heavily O-glycosylated.
    相似性Belongs to the adenosine and AMP deaminases family.
    功能Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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