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- bs-9340R-AP
- 2025年09月30日
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100ul
| 产品编号 | bs-9340R-AP |
| 英文名称 | MARCH6 Rabbit pAb, AP conjugated |
| 中文名称 | AP标记的膜相关环指蛋白6抗体 |
| 英文别名 | Doa10 homolog; E3 ubiquitin protein ligase MARCH6; MARCH 6; MARCH VI; MARCHVI; Membrane associated RING CH protein VI; Membrane associated ring finger(C3HC4) 6; Membrane associated RING finger protein 6; Protein TEB 4; Protein TEB4; RNF 176; RNF176; TEB 4; TEB4; RING finger protein 176; MARH6_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MARCH6 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with DIO2. |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi pass membrane protein. |
| 组织特异性 | Present in brain (at protein level). |
| 翻译后修饰 | Auto-ubiquitinated, which results in proteasomal degradation. |
| 相似性 | Contains 1 RING-CH-type zinc finger. |
| 功能 | E3 ubiquitin-protein ligase that promotes ubiquitination of DIO2, leading to its degradation. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MARCH6 (Membrane associated RING finger protein 6) belongs to the MARCH family, which contains at least seven membrane associated RING-CH (MARCH)proteins. MARCH proteins are E3 ubiquitin ligases and are located to subcellular membranes. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
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MARCH6 Rabbit pAb, AP conjugated(bs-9340R-AP)-100ul
￥2980
