- ￥2980
- Bioss
- bs-8630R-Bio
- 2025年09月30日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
TBX3 Rabbit pAb, Cy5.5 conjugated(bs-10266R-Cy5.5)-100ul
￥2980phospho-AKT1 (Ser129) Rabbit pAb, PE-Cy5.5 conjugated(bs-10996R-PE-Cy5.5)-100ul
￥2980phospho-c-Kit (Tyr730) Rabbit pAb, PerCP-Cy7 conjugated(bs-12914R-PerCP-Cy7)-100ul
￥2980MAPK organizer 1 Rabbit pAb, Biotin conjugated(bs-6722R-Bio)-100ul
￥2980
Anti-human RTN4 / NOGO (Ozanezumab Biosimilar)(BIO0240SM)-1mg/5mg/20mg
￥3200
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ul
| 产品编号 | bs-8630R-Bio |
| 英文名称 | SWAP70 Rabbit pAb, Biotin conjugated |
| 中文名称 | Biotin标记的开关相关蛋白70抗体 |
| 英文别名 | KIAA0640; 70kDa; AV235546; FLJ39540; HSPC321; SWA 70 protein; SWAP 70; SWAP switching B-cell complex 70kDa subunit; SWAP-70; Switch associated protein 70; Switch-associated protein 70; SWP70_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SWAP70 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Immunoglobulins > Class Switching Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins |
| 亚细胞定位 | Cytoplasm. Cell membrane. Nucleus. Cell projection > lamellipodium. In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus. In activated, class-switching B-cells it is associated with membrane IgG but not IgM. Localized to loose actin filament arrays located behind actively extending lamellipodia. |
| 组织特异性 | Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760). |
| 翻译后修饰 | Tyrosine-phosphorylated. |
| 相似性 | Contains 1 PH domain._x000D_ |
| 功能 | Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
SWAP70 Rabbit pAb, Biotin conjugated(bs-8630R-Bio)-100ul
￥2980
