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- Bioss
- bs-13044R-BF405
- 2025年09月30日
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100ul
| 产品编号 | bs-13044R-BF405 |
| 英文名称 | DZIP3 Rabbit pAb, BF405 conjugated |
| 中文名称 | BF405标记的E3泛素蛋白连接酶dzip3抗体 |
| 英文别名 | DAZ-interacting protein 3; E3 ubiquitin-protein ligase DZIP3; hRUL138; KIAA0675; RNA-binding ubiquitin ligase of 138 kDa; DZIP3_HUMAN. |
| 产品应用 | Flow-Cyt=2ug/Test, IF=1:100-500, ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human DZIP3 |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteasome / Ubiquitin > Ubiquitin E3 Enzymes > Other E3 Ligases Epigenetics and Nuclear Signaling > Cell cycle > Ubiquitin ligases Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Ubiquitylation |
| 亚基 | Interacts with DAZ proteins. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas. _x000D_ |
| 相似性 | Contains 1 RING-type zinc finger. _x000D_ |
| 功能 | E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA. |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DZIP3 is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events. |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {2ug/Test} |
| {IF} | {1:100-500} |
| {ICC/IF} | {1:100-500} |
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DZIP3 Rabbit pAb, BF405 conjugated(bs-13044R-BF405)-100ul
￥2980
