M Cadherin Rabbit pAb, AP conjugated(bs-6678R-AP)-100ul

M Cadherin Rabbit pAb, AP conj

ugated(bs-6678R-AP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-6678R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-6678R-AP
    英文名称M Cadherin Rabbit pAb, AP conjugated
    中文名称AP标记的M钙粘附分子抗体
    英文别名M-Cadherin; Cadherin 14; Cadherin 15; Cadherin 3; Cadherin14; Cadherin15; Cadherin3; CCAD; CDH 14; CDH 15; CDH 3; CDH14; CDH15; CDH3; CDHM; MCAD; Muscle cadherin; Myotubule cadherin; CAD15_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human M-Cadherin
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell differentiation

    Neuroscience > Cell Adhesion Proteins > Membrane Proteins

    Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cadherins

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calcium Binding Proteins

    亚细胞定位Type 1 membrane protein.
    组织特异性Expressed in the brain and cerebellum.
    相似性Contains 5 cadherin domains.
    功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cadherins are a family of transmembrane glycoproteins that play a key role in Calcium dependent cell-cell adhesion. Several members of the cadherin family have been identified so far, including E- (epithelial), P- (placental), N- (neuronal) and M- (muscle) cadherin. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. M-Cadherin is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

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