RAB7L1 Rabbit pAb, AP conjugated(bs-19719R-AP)-100ul

RAB7L1 Rabbit pAb, AP conjugat

ed(bs-19719R-AP)-100ul
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  • ￥2980
  • Bioss已认证
  • bs-19719R-AP
  • 2025年09月30日
  • 产品信息以Bioss网站为准
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北京博奥森生物技术有限公司
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    • 规格：

      100ul

    产品编号bs-19719R-AP
    英文名称RAB7L1 Rabbit pAb, AP conjugated
    中文名称AP标记的ras基因相关蛋白RAB7样蛋白1抗体
    英文别名RAB7L_HUMAN; RAB29; DKFZp686P1051; Rab 7 like protein 1; RAB 7L; Rab7 like protein 1; RAB7 member RAS oncogene family like 1; RAB7L; Ras related protein Rab 7L1; Ras-related protein Rab-7L1; Ras related protein Rab7L1.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human RAB7L1
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Ras Family

    亚细胞定位Cell membrane; Lipid-anchor; Cytoplasmic side.
    翻译后修饰In case of Salmonella enterica serovar Typhimurium (S.Typhimurium) infection, is proteolytically cleaved between Gly-41 and Val-42 by the GtgE viral protease encoded on the Gifsy-2 lysogen bacteriophage, which therefore prevents the recruitment of RAB29 to S.Typhimurium-containing vacuoles. In contrast, no proteolytically cleavage is detected in S.Typhi-infected cells (PubMed:22042847).
    相似性Belongs to the small GTPase superfamily. Rab family.
    功能Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.
    保存条件Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}

     

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