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phospho-HSD17B13 (Ser33) Rabbi

t pAb, PerCP-Cy7 conjugated(bs-22308R-PerCP-Cy7)-100ul
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  • ¥2980
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  • bs-22308R-PerCP-Cy7
  • 2025年09月30日
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      100ul

    产品编号bs-22308R-PerCP-Cy7
    英文名称phospho-HSD17B13 (Ser33) Rabbit pAb, PerCP-Cy7 conjugated
    中文名称PerCP-Cy7标记的磷酸化17β羟基类固醇脱氢酶13抗体
    英文别名HSD17B13(phospho S33); HSD17B13(phospho Ser33); phospho-HSD17B13(S33); p-HSD17B13(Ser33); 17-beta-HSD 13; 17-beta-hydroxysteroid dehydrogenase 13; DHB13_HUMAN; HMFN0376; Hsd17b13; SCDR9; Short-chain dehydrogenase/reductase 9; UNQ497/PRO1014.
    产品应用Flow-Cyt=1ug/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    抗体来源Rabbit
    免疫原KLH conjugated synthesised phosphopeptide derived from human HSD17B13 around the phosphorylation site of Ser33
    亚型IgG
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA and 0.02% Proclin300.
    研究领域

    Cell Biology > Other Antibodies > Oxidative Stress

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Signal Transduction > Metabolism > Energy Metabolism

    亚细胞定位Secreted.
    相似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    功能Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis.
    保存条件Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料17 beta-HSD13 (17 beta hydroxysteroid dehydrogenase type 13), also designated Short-chain dehydrogenase/reductase 9 (SCDR9), belongs to the 17 beta-HSD family of proteins, which regulate the availability of steroids within various tissues throughout the body. 17 beta-HSD13 is a 300 amino acid secreted protein that is highly expressed in liver and is also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. The gene encoding 17 beta-HSD13 maps to chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

     

    应用推荐稀释比例
    {Flow-Cyt}{1ug/Test}

     

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    图标文献和实验
    相关实验
    • v468 chapter 5 糖原合成酶激酶-3 的抑制

      at 10, 25, and 50 μM). At 24 h post-treatment, celllysates were obtained; SDS-PAGE and Western blotting were performed as described in Section 3, Methods. AR-A014418dose-dependent decreases of phospho-β-catenin (Ser33/37) and phospho-glycogen synthase

    • v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平

      4 ). 2. Other antibodies used were b-catenin (phospho-Thr41/Ser37/Ser33) (#9561; Cell Signaling Technology), b-catenin (#9562;Cell Signaling Technology), CRMP2 (pT514/509) (#PB-043; Kinasource, Dundee, Scotland) and CRMP2 (#AB-042;Kinasource). 3. Blocking buffer

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