- ￥2980
- Bioss
- bs-4228R-PE
- 2025年12月04日
- 产品信息以Bioss网站为准
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100ul
| 产品编号 | bs-4228R-PE |
| 英文名称 | VLDL Receptor Rabbit pAb, PE conjugated |
| 中文名称 | PE标记的极低密度脂蛋白受体抗体 |
| 英文别名 | Very low density lipoprotein receptor; VLDL R; VLDLR; VLDL-R; VLDLRCH. |
| 产品应用 | ICC/IF=1:100-500 Not yet tested in other applications. |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human VLDL Receptor |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Binds to the extracellular matrix protein Reelin. Interacts with VLDLR. Interacts with SNX17. Interacts with DAB1. Receptor for the minor-group human rhinoviruses (HRVs); binds protein VP1 through the second and third LDL-receptor class A domains. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein. |
| 组织特异性 | Abundant in heart and skeletal muscle; also ovary and kidney; not in liver. |
| 翻译后修饰 | Abundant in heart and skeletal muscle; also ovary and kidney; not in liver. |
| 相似性 | Contains 3 EGF-like domains. Contains 8 LDL-receptor class A domains. Contains 6 LDL-receptor class B repeats. |
| 功能 | Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). |
| 保存条件 | Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | VLDL (very low density lipoprotein) cholesterol is one of the three major types of cholesterol found in blood. VLDL receptor plays an essential role in triglyceride metabolism. It binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. |
| 应用 | 推荐稀释比例 |
| {ICC/IF} | {1:100-500} |
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VLDL Receptor Rabbit pAb, PE conjugated(bs-4228R-PE)-100ul
￥2980
