Elab Fluor® 647 Anti-Mouse CD2

CD205, Cd205流式抗体, CD205抗体, DEC-205, DEC205, Ly-75, Ly75, 小鼠CD205, 小鼠CD205流式抗体, AN00844

Membrane

NLDC-145

Rat IgG2a, κ

咨询

CD205, also known as DEC-205, is a 205 kD integral membrane protein homologous to the macrophage mannose receptor. It is a type I cell surface protein that belong to the C-type lectin family.  CD205 is expressed at high levels by dendritic cells and thymic epithelial cells.  It is also expressed by a number of other cell types, such as B lymphocytes, macrophages, Langerhans cells, bone marrow stromal cells, granulocytes, epithelial cells of pulmonary airways, and the capillaries of the brain.  CD205 is a novel endocytic receptor used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to specialized antigen processing.  It mediates antigen uptake and presentation and cross-presentation to T cells.  It has been reported that CD205 acts as a recognition receptor for dying cells, potentially provides an important pathway for the uptake of self-antigen in the intrathymic environment, and is involved in peripheral tolerance.  Antibody-mediated antigen-targeting via the DEC-205 receptor increases the efficiency of vaccination for T cell immunity.

CD205

Q60767

Rat

Mouse

Monoclonal

Elab Fluor^® 647 Rat IgG2a, κ Isotype Control[2A3]

FCM

Liquid

5 μL/Test

Elab Fluor^®647

Elab Fluor^® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

冰袋

17076