- ￥880
- Bioss
- bs-19721P
- 2026年10月10日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-19721P |
| 英文名称 | RABEP1 Antibody Blocking Peptide |
| 中文名称 | RABEP1蛋白封闭多肽 |
| 英文别名 | Neurocrescin; Rab GTPase binding effector protein 1; RAB5EP; Rabaptin 4; Rabaptin 5; Rabaptin 5alpha; RABPT5; RABPT5A; Renal carcinoma antigen NY REN 17; Renal carcinoma antigen NYREN17. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation Signal Transduction > Signaling Pathway > G Protein Signaling > Small G Proteins > Regulators |
| 亚基 | Homodimer when bound to RAB5A. Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2. Interacts with ECM29. |
| 亚细胞定位 | Cytoplasm. Early endosome. Recycling endosome |
| 翻译后修饰 | Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. |
| 相似性 | Belongs to the rabaptin family. |
| 功能 | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RABEP1 is a Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. It is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. |
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RABEP1 | Rabaptin-5 Ab Blocking Peptide(bs-19721P)-500ug
￥880
