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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -20°C. Stable for one year after shipment.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
WB, ELISA
- 靶点:
P glycoprotein
- 抗体英文名:
P glycoprotein Recombinant monoclonal antibody
- 抗体名:
P glycoprotein Recombinant monoclonal antibody
- 规格:
50ul/100ul/150ul
| 规格: | 50ul | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥2480.0 |
| 规格: | 150ul | 产品价格: | ¥3280.0 |
经过测试的应用
| Positive WB detected in | PC-3 cells, HuH-7 cells, HepG2 cells, HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
84295-3-RR targets P glycoprotein in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| 别名 | ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1 |
| 计算分子量 | 1280 aa, 142 kDa |
| 观测分子量 | 130-150 kDa |
| GenBank蛋白编号 | BC130424 |
| 基因名称 | P glycoprotein |
| Gene ID (NCBI) | 5243 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P08183 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.
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文献和实验【分享】Glycoprotein Analysis in Biomedicine
Spectrometry of Glycoprotein Oligosaccharides Gunnar Hansson; Hasse Karlsson pp. 47-54 5. Microscale Sequencing of N-Linked Oligosaccharides of Glycoproteins Using Hydrazinolysis, Bio-Gel P-4, and Sequential Exoglycosidase Digestion Tsuguo Mizuochi pp
Expression of EGF and HIV Envelope Glycoprotein
were to examine the secretion in Pichia pastoris of a simple polypeptide and a complex glycoprotein, ultimately the work yielded insights into a wide range of issues affecting gene expression in P. pastoris , from foreign gene transcription to multicopy selection
倍稀释℃,d=1)S = 各浓℃细胞病变比率之和 实验室重组腺病毒常用质粒:病毒骨架质粒:pAdEasy-1, pAdEasy-2 穿梭质粒:p-Shuttle, p-Shuttle-CMV, pAdTrack, pAdTrack-CMV
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