- ￥1350 - 3000
- Proteintech
- 27414-1-AP
- 2025年10月09日
- WB, ELISA
- Rabbit
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human SOX4 protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, ELISA
- 靶点：
SOX4
- 抗体英文名：
SOX4 Polyclonal antibody
- 抗体名：
SOX4 Polyclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1350.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2200.0 |
| 规格： | 150ul | 产品价格： | ￥3000.0 |
经过测试的应用
| Positive WB detected in | A549 cells, HL-60 cells, HepG2 cells, K-562 cells, MDA-MB-231 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
27414-1-AP targets SOX4 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA |
| 文献引用应用 | WB |
| 经测试反应性 | human |
| 文献引用反应性 | human |
| 免疫原 |
CatNo: Ag26583 Product name: Recombinant human SOX4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 70-160 aa of BC072668 Sequence: SQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGG |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | SRY (sex determining region Y)-box 4 |
| 别名 | Transcription factor SOX-4, EVI16, CSS10 |
| 计算分子量 | 474 aa, 47 kDa |
| 观测分子量 | 47 kDa |
| GenBank蛋白编号 | BC072668 |
| 基因名称 | SOX4 |
| Gene ID (NCBI) | 6659 |
| RRID | AB_3085955 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q06945 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors that play key roles in the regulation of stemness, differentiation, progenitor cell development, and multiple developmental pathways. A single-exon gene encodes the SOX4 protein and contains a highly conserved high-mobility group (HMG) DNA binding domain related to the TCF/LEF family of transcription factors that play important roles in the Wnt pathway. SOX4 is expressed in stem cells, and modulates stem cell activation and likely also plays a role in stem cell maintenance, possibly through activation of expression of SOX2 (PMID: 23764001, 31445218). The calculated molecular weight of SOX4 is 47 kDa.
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文献和实验| Species | Application | Title |
|---|---|---|
| human | WB | Adv Sci (Weinh) DNA Sensor ABCF1 Phase Separates With cccDNA to Inhibit Hepatitis B Virus ReplicationAuthors - Caiyue Ren |
| human | WB | Adv Sci (Weinh) Exosomal CCT6A Secreted by Cancer-Associated Fibroblasts Interacts with β-Catenin to Enhance Chemoresistance and Tumorigenesis in Gastric CancerAuthors - Hui Sun |
| human | WB | Int J Mol Sci Preclinical Repurposing of Sitagliptin as a Drug Candidate for Colorectal Cancer by Targeting CD24/CTNNB1/SOX4-Centered Signaling HubAuthors - Jing-Wen Shih |
| human | WB | Oral Dis USP14 promotes the cancer stem-like cell properties of OSCC via promoting SOX2 deubiquitinationAuthors - Chang Liu |
| human | WB | Cell Signal The roles and mechanisms of TGFB1 in acute myeloid leukemia chemoresistanceAuthors - Xue Liang |
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