- ￥2800
- Proteintech
- CL594-66747
- 2025年10月09日
- IF/ICC
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human AR protein
- 亚型：
IgG2a
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite®594 Fluorescent Dye
- 适应物种：
Human
- 宿主：
Mouse
- 应用范围：
IF/ICC
- 靶点：
AR
- 抗体英文名：
CoraLite®594-conjugated AR Monoclonal antibody
- 抗体名：
CoraLite®594-conjugated AR Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF/ICC detected in | LNCaP cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-66747 targets AR in IF/ICC applications and shows reactivity with Human samples.
| 经测试应用 | IF/ICC |
| 经测试反应性 | Human |
| 免疫原 |
CatNo: Ag17291 Product name: Recombinant human AR protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-285 aa of BC132975 Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPL |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | androgen receptor |
| 别名 | AIS, androgen receptor, AR, DHTR, Dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM |
| 计算分子量 | 914 aa, 99 kDa |
| 观测分子量 | 110-120 kDa |
| GenBank蛋白编号 | BC132975 |
| 基因名称 | AR |
| Gene ID (NCBI) | 367 |
| RRID | AB_2934741 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P10275 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
AR, also named as DHTR and NR3C4, belongs to the nuclear hormone receptor family and NR3 subfamily. AR is a ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. AR is activated, but not phosphorylated, by HIPK3. Defects in AR are the cause of androgen insensitivity syndrome (AIS), previously known as testicular feminization syndrome (TFM), which is an X-linked recessive form of pseudohermaphroditism due end-organ resistance to androgen. Defects in AR are the cause of spinal and bulbar muscular atrophy X-linked type 1 (SMAX1) which also known as Kennedy disease. Defects in AR may play a role in metastatic prostate cancer. Defects in AR are the cause of androgen insensitivity syndrome partial (PAIS) which also known as Reifenstein syndrome. AR exists various isoforms with MV 110-120 kDa and 75-80 kDa. (PMID: 19244107 )
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文献和实验1试剂 (1) 小鼠腹水 (2) 饱和硫酸铵溶液的配制: 称(NH4)2SO4(AR)400～425克，以50～80℃之蒸馏水500ml溶解，搅拌20分钟，趁热过滤。冷却后以浓氨水(15N NH4OH)调PH至7.4。配制好的饱和硫酸铵，瓶底应有结晶析出。 (3) 0.06M, PH4.8醋酸盐缓冲液配制:) `0 }2 j2 v. ] ^ 贮存液:' ~. o6 \5 o5 W1 [7 h A液：0.06M NaAc：无水NaAc0.49218克，加蒸馏
Anti-Digoxin 产品详情 Dylight 594标记小鼠抗地高辛Digoxin单克隆抗体 Dylight 594-conjugated IgG Fraction Monoclonal Mouse Anti-Digoxin 产品详情
一、 试剂及材料（试剂盒包含内容） 1. 膜芯片---（RayBio®Human Cytokine Antibody Array membranes ，2/4/8张膜） 2. 生物素标记抗体---（Biotin-Conjugated Anti-Cytokines， 1/2/4 管， 每2张膜配1个管） 3. 1000×HRP-链霉亲和素---（HRP-Conjugated Streptavidin，1管） 4. 1X封闭缓冲液---（Blocking Buffer
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