- ￥2800
- Proteintech
- CL594-66895
- 2025年10月09日
- IF/ICC
- Mouse
- Human, rat, mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human a-Actinin protein
- 亚型：
IgG2b
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
CoraLite®594 Fluorescent Dye
- 适应物种：
Human, rat, mouse
- 宿主：
Mouse
- 应用范围：
IF/ICC
- 靶点：
Alpha Actinin
- 抗体英文名：
CoraLite®594-conjugated Alpha Actinin Monoclonal antibody
- 抗体名：
CoraLite®594-conjugated Alpha Actinin Monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF/ICC detected in | C2C12 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL594-66895 targets Alpha Actinin in IF/ICC applications and shows reactivity with Human, rat, mouse samples.
| 经测试应用 | IF/ICC |
| 经测试反应性 | Human, rat, mouse |
| 免疫原 |
CatNo: Ag28383 Product name: Recombinant human a-Actinin protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 543-892 aa of BC015766 Sequence: EIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLSHLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARMAPYTGPDSVPGALDYMSFSTALYGESDL |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | actinin, alpha 1 |
| 别名 | actinin, alpha 1, ACTN1, Alpha Actinin, Alpha actinin 1, F actin cross linking protein, FLJ40884, FLJ54432, Non muscle alpha actinin 1 |
| 计算分子量 | 103 kDa |
| 观测分子量 | 100-105 kDa |
| GenBank蛋白编号 | BC015766 |
| 基因名称 | Alpha Actinin |
| Gene ID (NCBI) | 87 |
| RRID | AB_3084734 |
| 偶联类型 | CoraLite®594 Fluorescent Dye |
| 最大激发/发射波长 | 588 nm / 604 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P12814 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Alpha Actinins are highly conserved actin-binding proteins that form antiparallel homodimers with the actin-binding domains on each end of the molecule, allowing crosslinking of actin molecules. There are four alpha actinin isoforms identified: two ubiquitously expressed cytoskeletal isoforms (ACTN1 and ACTN4) and two striated muscle-specific sarcomeric isoforms (ACTN2 and ACTN3). ACTN1 is also alternatively spliced to form smooth muscle or brain specific isoforms. This antibody recognize endogenous ACTN1, while it may cross-react with ACTN2 and ACTN4.
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文献和实验【共享】某机构发表的核酸相关研究的文章（EST,SNP等），PDF全文下载
A (2006) Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: Modes of action and impact on lethality J Pharmacol Exp Ther 318: 762-771 Elsharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M
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