- ￥600 - 1320
- Proteintech
- FITC-65229
- 2025年10月09日
- FC
- Mouse
- rat
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG2a, kappa
- 保存条件：
Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
FITC Plus Fluorescent Dye
- 适应物种：
rat
- 宿主：
Mouse
- 应用范围：
FC
- 靶点：
CD11b
- 抗体英文名：
FITC Plus Anti-Rat CD11b (OX42)
- 抗体名：
FITC Plus Anti-Rat CD11b (OX42)
- 规格：
25ug/100ug
| 规格： | 25ug | 产品价格： | ￥600.0 |
|---|---|---|---|
| 规格： | 100ug | 产品价格： | ￥1320.0 |
经过测试的应用
| Positive FC detected in | rat bone marrow cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
FITC-65229 targets CD11b in FC applications and shows reactivity with rat samples.
| 经测试应用 | FC |
| 文献引用应用 | FC |
| 经测试反应性 | rat |
| 文献引用反应性 | rat |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG2a, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | integrin alpha M |
| 别名 | integrin alpha M, Itgam, OX42 |
| 计算分子量 | 127 kDa |
| GenBank蛋白编号 | NM_012711 |
| 基因名称 | CD11b |
| Gene ID (NCBI) | 25021 |
| RRID | AB_2924146 |
| 偶联类型 | FITC Plus Fluorescent Dye |
| 最大激发/发射波长 | 495 nm / 524 nm |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | Q9JI30 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b (integrin alpha M or CR3A) and CD11c (integrin alpha X) are members of the integrin alpha chain family and can form α/β heterodimers with CD18 (integrin β2). CD11b/CD18 is a receptor for the complement protein fragment C3bi, and is also a receptor for fibrinogen, factor X, and ICAM1 (PMID: 2971974; 15485828). CD11c/CD18 acts as a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533). The OX-42 antibody recognizes a common epitope shared between CD11b and CD11c. It binds to C3bi receptor and is known to block C3bi binding (PMID: 3512425; 8449218).
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文献和实验| Species | Application | Title |
|---|---|---|
| rat | FC | Mol Med Rep Discovery of microglia gonadotropin‑releasing hormone receptor and its potential role in polycystic ovarian syndromeAuthors - Fan Wang |
| rat | FC | Biomater Res CD62E- and ROS-Responsive ETS Improves Cartilage Repair by Inhibiting Endothelial Cell Activation through OPA1-Mediated Mitochondrial HomeostasisAuthors - Pengcheng Tu |
| FC | Heliyon Peimine promotes microglial polarization to the M2 phenotype to attenuate drug-resistant epilepsy through suppressing the TLR4/NF-κB/HIF-1α signaling pathway in a rat model and in BV-2 microgliaAuthors - Chongchong Liu |
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