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Atlantic Blue™ Anti-Human CD11

c (3.9) AB-65086
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  • ¥1100 - 2740
  • Proteintech已认证
  • AB-65086
  • 2025年10月09日
  • FC
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG1, kappa

    • 保存条件

      Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    • 克隆性

      Monoclonal

    • 标记物

      Atlantic Blue™ Fluorescent Dye

    • 适应物种

      Human

    • 宿主

      Mouse

    • 应用范围

      FC

    • 靶点

      CD11c

    • 抗体英文名

      Atlantic Blue™ Anti-Human CD11c (3.9)

    • 抗体名

      Atlantic Blue™ Anti-Human CD11c (3.9)

    • 规格

      25tests/100tests

    规格:25tests产品价格:¥1100.0
    规格:100tests产品价格:¥2740.0

    经过测试的应用

    Positive FC detected inhuman PBMCs
    Planning an IHC experiment? We recommend our IHCeasy CD11c Ready-To-Use IHC Kit. CD11c primary antibody included.

    推荐稀释比

    应用推荐稀释比
    Flow Cytometry (FC)FC : 5 ul per 10^6 cells in 100 μl suspension
    This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    AB-65086 targets CD11c in FC applications and shows reactivity with Human samples.

    经测试应用 FC
    经测试反应性 Human
    免疫原

    fusion protein

    宿主/亚型 Mouse / IgG1, kappa
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 integrin, alpha X (complement component 3 receptor 4 subunit)
    别名 CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6
    计算分子量 1169 aa, 129 kDa
    GenBank蛋白编号BC038237
    基因名称 CD11c
    Gene ID (NCBI) 3687
    ENSEMBL Gene IDENSG00000140678
    RRIDAB_2935163
    偶联类型 Atlantic Blue™ Fluorescent Dye
    最大激发/发射波长404 nm / 458 nm
    形式Liquid
    纯化方式Affinity purification
    UNIPROT IDP20702
    储存缓冲液 PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
    储存条件Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

    背景介绍

    Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

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    图标文献和实验
    相关实验
    • Immunostaining with Anti-Digoxigenin Alkaline Phosphatase

      Materials Anti-digoxigenin-AP conjugate (Roche #11093274910, 150U/200 uL, $168) Levamisole (Sigma #T1512, 2 g, $10)  (blocks endogenous phosphatase activity) BCIP (Roche #11383221001, 3 mL, $49) NBT (Roche #11383213001, 3 mL, $48)

    • Protocol for anti-HA antibody Western Blotting

      SJF 4/00 1) Run gel (in 1:10 running/transfer buffer(10x) and H2O for a total of 1litre) at 150 volts until leading bromophenol blue band is nearing the bottom edge of the glass plates or according to the expected migration of the protein

    • Protocol for anti-HA antibody Western Blotting

        1) Run gel (in 1:10 running/transfer buffer(10x) and H2O for a total of 1litre) at 150 volts until leading bromophenol blue band is nearing the bottom edge of the glass plates or according to the expected migration of the protein

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