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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human RGS4 protein
- 亚型:
IgG1
- 保存条件:
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
CoraLite® Plus 488 Fluorescent Dye
- 适应物种:
human, rat, mouse, pig
- 宿主:
Mouse
- 应用范围:
WB
- 靶点:
RGS4
- 抗体英文名:
CoraLite® Plus 488-conjugated RGS4 Monoclonal antibody
- 抗体名:
CoraLite® Plus 488-conjugated RGS4 Monoclonal antibody
- 规格:
100ul
经过测试的应用
| Positive WB detected in | C6 cells, Neuro-2a cells, Raji cells, SH-SY5Y cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-66441 targets RGS4 in WB applications and shows reactivity with human, rat, mouse, pig samples.
| 经测试应用 | WB |
| 经测试反应性 | human, rat, mouse, pig |
| 免疫原 |
CatNo: Ag6029 Product name: Recombinant human RGS4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-205 aa of BC051869 Sequence: MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | regulator of G-protein signaling 4 |
| 别名 | DKFZp761F1924, RGP4, RGS4, SCZD9 |
| 计算分子量 | 23 kDa |
| 观测分子量 | 34 kDa |
| GenBank蛋白编号 | BC051869 |
| 基因名称 | RGS4 |
| Gene ID (NCBI) | 5999 |
| RRID | AB_3084246 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P49798 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Regulator of G protein signaling (RGS) proteins are a large family of highly diverse, multifunctional signaling proteins. RGS4 is one of seven members of a classic R4 RGS protein that accelerates the GTPase activity of the Gai/o and Gaq/11 family members. RGS4 is highly expressed in multiple brain regions including the cerebral cortex, amygdala, hippocampus, and striatum. Extensive studies have demonstrated that RGS4 plays an important role in regulating smooth muscle contraction, cardiomyocyte development, neural plasticity and psychiatric disorders.
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