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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG1, kappa
- 保存条件:
2-8°C Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
5CFLX
- 适应物种:
Human
- 宿主:
Mouse
- 应用范围:
Single Cell (Intra), Single Cell
- 靶点:
CD35
- 抗体英文名:
MultiPro® 5CFLX Anti-Human CD35 (E11)
- 抗体名:
MultiPro® 5CFLX Anti-Human CD35 (E11)
- 规格:
10ug
经过测试的应用
| Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
| Positive Single Cell detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| SINGLE CELL (INTRA) | <0.5ug/test |
| SINGLE CELL | <0.5ug/test |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
产品信息
G65254-1-5C targets CD35 in Single Cell (Intra), Single Cell applications and shows reactivity with Human samples.
| 经测试应用 | Single Cell (Intra), Single Cell |
| 经测试反应性 | Human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG1, kappa |
| 抗体类别 | Oligo Conjugate |
| 产品类型 | Monoclonal |
| 全称 | MultiPro® 5CFLX Anti-Human CD35 (E11) |
| 别名 | C3b/C4b receptor, C3BR, CD35, Complement receptor type 1, CR1, KN |
| 计算分子量 | 224 kDa |
| GenBank蛋白编号 | NM_000573 |
| 基因名称 | CR1 |
| Gene ID (NCBI) | 1378 |
| ENSEMBL Gene ID | ENSG00000203710 |
| RRID | AB_3673940 |
| 偶联类型 | 5CFLX |
| 完整寡核苷酸序列 | CGGAGATGTGTATAAGAGACAGAATGAATTGGATTCGCCCATATAAGAAA |
| 条形码序列 | AATGAATTGGATTCG |
| 形式 | Liquid |
| UNIPROT ID | P17927 |
| 储存缓冲液 | PBS with 1mM EDTA and 0.09% sodium azide , pH 7.3. |
| 储存条件 | 2-8°C Stable for one year after shipment. |
背景介绍
CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes.
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文献和实验MY9,H153,L4F3 M,BM gp67 ? CD34 MY10,ICH3 BM gp105~120 生长因子受体?调控早期造血 CD35 TO5,E11,(CR1) G,M,B
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