- ￥1500 - 3280
- Proteintech
- 86038-1-RR
- 2025年10月09日
- WB, IF/ICC, ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -20°C. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, IF/ICC, ELISA
- 靶点：
CCR3
- 抗体英文名：
CCR3 Recombinant monoclonal antibody
- 抗体名：
CCR3 Recombinant monoclonal antibody
- 规格：
50ul/100ul/150ul
| 规格： | 50ul | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥2480.0 |
| 规格： | 150ul | 产品价格： | ￥3280.0 |
经过测试的应用
| Positive WB detected in | A375 cells, THP-1 cells, Jurkat cells, HUVEC cells, U-87 MG cells |
| Positive IF/ICC detected in | K-562 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:250-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
86038-1-RR targets CCR3 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, ELISA |
| 经测试反应性 | human |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-C motif) receptor 3 |
| 别名 | C C chemokine receptor type 3, C C CKR 3, C C CKR3, C-C chemokine receptor type 3, CC CKR 3 |
| 计算分子量 | 355 aa, 41 kDa |
| 观测分子量 | 53 kDa |
| GenBank蛋白编号 | BC110297 |
| 基因名称 | CCR3 |
| Gene ID (NCBI) | 1232 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P51677 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CCR3 (C-C Motif Chemokine Receptor 3), also known as CD193, is a G protein-coupled receptor (GPCR) primarily involved in immune cell trafficking and inflammation regulation and highly expressed in eosinophils and basophils, with detectable levels in Th2 cells, airway epithelial cells, and subsets of monocyte-derived dendritic cells (PMID: 21077277). Ligand-induced CCR3 internalization is required for eosinophil shape change and actin polymerization but not for calcium mobilization or desensitization (PMID: 12532103).
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