CD22 重组单克隆抗体  86128-1-RR

CD22 重组单克隆抗体 86128-1-RR

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  • ¥1500 - 3280
  • Proteintech已认证
  • 86128-1-RR
  • 2025年10月09日
  • WB, IHC, ELISA
  • Rabbit
  • mouse
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    • 详细信息
    • 技术资料
    • 亚型

      IgG

    • 保存条件

      Store at -20°C. Stable for one year after shipment.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      mouse

    • 宿主

      Rabbit

    • 应用范围

      WB, IHC, ELISA

    • 靶点

      CD22

    • 抗体英文名

      CD22 Recombinant monoclonal antibody

    • 抗体名

      CD22 Recombinant monoclonal antibody

    • 规格

      50ul/100ul/150ul

    规格:50ul产品价格:¥1500.0
    规格:100ul产品价格:¥2480.0
    规格:150ul产品价格:¥3280.0

    经过测试的应用

    Positive WB detected inA20 cells, mouse spleen tissue
    Positive IHC detected inmouse spleen tissue
    Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

    推荐稀释比

    应用推荐稀释比
    Western Blot (WB)WB : 1:2000-1:10000
    Immunohistochemistry (IHC)IHC : 1:5000-1:20000
    It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
    Sample-dependent, Check data in validation data gallery.

    产品信息

    86128-1-RR targets CD22 in WB, IHC, ELISA applications and shows reactivity with mouse samples.

    经测试应用 WB, IHC, ELISA
    经测试反应性 mouse
    免疫原

    CatNo: Eg1324

    Product name: recombinant mouse CD22 protein

    Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

    Tag: C-6*HIS

    Domain: 22-708 aa of NM_001043317.2

    Sequence: SANDWTVDHPQTLFAWEGACIRIPCKYKTPLPKARLDNILLFQNYEFDKATKKFTGTVLYNATKTEKDPESELYLSKQGRVTFLGNRIDNCTLKIHPIRANDSGNLGLRMTAGTERWMEPIHLNVSEKPFQPYIQMPSEIRESQSVTLTCGLNFSCFGYDILLKWFLEDSEITSITSSVTSITSSVTSSIKNVYTESKLTFQPKWTDHGKSVKCQVQHSSKVLSERTVRLDVKYTPKLEIKVNPTEVEKNNSVTMTCRVNSSNPKLRTVAVSWFKDGRPLEDQELEQEQQMSKLILHSVTKDMRGKYRCQASNDIGPGESEEVELTVHYAPEPSRVHIYPSPAEEGQSVELICESLASPSATNYTWYHNRKPIPGDTQEKLRIPKVSPWHAGNYSCLAENRLGHGKIDQEAKLDVHYAPKAVTTVIQSFTPILEGDSVTLVCRYNSSNPDVTSYRWNPQGSGSVLKPGVLRIQKVTWDSMPVSCAACNHKCSWALPVILNVHYAPRDVKVLKVSPASEIRAGQRVLLQCDFAESNPAEVRFFWKKNGSLVQEGRYLSFGSVSPEDSGNYNCMVNNSIGETLSQAWNLQVLYAPRRLRVSISPGDHVMEGKKATLSCESDANPPISQYTWFDSSGQDLHSSGQKLRLEPLEVQHTGSYRCKGTNGIGTGESPPSTLTVYYSPETIGKR

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 CD22 antigen
    别名 B-cell receptor CD22, BL-CAM, B-lymphocyte cell adhesion molecule, Lyb-8, Sialic acid-binding Ig-like lectin 2
    计算分子量97kDa
    观测分子量 120-150 kDa
    GenBank蛋白编号NM_001043317.2
    基因名称 Cd22
    Gene ID (NCBI) 12483
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purification
    UNIPROT IDP35329-1
    储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
    储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

    背景介绍

    CD22, also known as Siglec-2 (sialic acid binding Ig-like lectin 2) or BL-CAM (B-lymphocyte cell adhesion molecule), is a 130-140 kDa, B-cell restricted, type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The expression of CD22 is developmentally regulated. It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation. Cell surface expression is lost during terminal differentiation into plasma cell and after B-cell activation. CD22 is an inhibitory receptor for B-cell receptor (BCR) signalling, preferentially binds to alpha-2,6-linked sialic acid and mediates B-cell B-cell interactions. It plays a crucial role in activation and differentiation of the B-cell.

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