- ￥1000 - 2540
- Proteintech
- 65189-1-Ig
- 2025年10月09日
- FC
- Rat
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1, kappa
- 保存条件：
Store at 2-8°C. Stable for one year after shipment.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
mouse
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
CD41
- 抗体英文名：
Anti-Mouse CD41 (MWReg30)
- 抗体名：
Anti-Mouse CD41 (MWReg30)
- 规格：
100ug/500ug
| 规格： | 100ug | 产品价格： | ￥1000.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥2540.0 |
经过测试的应用
| Positive FC detected in | C57BL/6 mouse peripheral blood platelets |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65189-1-Ig targets CD41 in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | integrin alpha 2b |
| 别名 | Itga2b, GpIIb, integrin alpha 2b, MWReg30 |
| GenBank蛋白编号 | BC120493 |
| 基因名称 | CD41 |
| Gene ID (NCBI) | 16399 |
| RRID | AB_3084902 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Purified by protein-G affinity chromatography |
| UNIPROT ID | Q9QUM0 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
The integrins are a superfamily of cell adhesion receptors that bind to extracellular matrix ligands, cell-surface ligands, and soluble ligands (PMID: 17543136). They are transmembrane αβ heterodimers and at least 24 distinct integrin heterodimers are formed by the combination of 18 α and eight β known subunits (PMID: 17543136; 20029421). In addition to mediating cell adhesion, integrins also play important roles in modulating signal transduction pathways that control cellular responses including migration, proliferation, differentiation, and apoptosis (PMID: 19118207). Integrin alpha-IIb (ITGA2B, CD41) is expressed on platelets, megakaryocytes and some hematopoietic progenitor cells (PMID: 11934866). This protein undergoes post-translational cleavage to yield disulfide linked light beta (25 kDa) and heavy alpha (125 kDa) chains, which join with integrin beta3 (CD61) to form a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. CD41/CD61 is crucial for platelet aggregation through binding of soluble fibrinogen.
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文献和实验实验步骤 1. Using the AbC™ Anti-Mouse Bead Kit 1) Completely resuspend the AbC™ capture beads (Component A) and negative beads (Component B) by gently vortexing for 30 seconds before use. 2) Label
49e/CD29、CD49f/CD29、CD51/CD29、CD11a/CD18、CD11b/CD18、CD11c/CD18、CD41/CD61、CD51/CD61、CD49f/CD104、CD2、CD4、CD8、CD28、CD31、CD50、CD54、CD56、CD58、CD80、CD102、CD106、CD62L、CD62P、CD62E、CD15、CD15s、CD44等。 （2）B表示CD命名范围中属IGSF结构的分子，如CD79a、CD79b、CD1、CD
因子文章，其中不乏 Nature、Cell 等顶级期刊。研究细胞涵盖 PBMC、神经、小肠等多种类型，研究方向主要涉及构建细胞图谱、发育分化、癌症和免疫研究等。已发表 10x 单细胞转录组文章（影响因子分布＆文章类型）适用研究领域发育及分化新型细胞发现构建细胞图谱细胞异质性研究免疫反应定点编辑基因的细胞水平研究适用细胞类型生殖细胞、胚胎细胞、神经细胞、免疫细胞、肿瘤细胞、干细胞、其他原代细胞样品要求样本类型：动物细胞 - 单细胞悬液；植物细胞 - 原生质体。细胞状态：细胞直径＜30 μm；细胞活性＞90%；细胞
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