- ￥2800
- Proteintech
- CL488-84468-4
- 2025年10月09日
- IF/ICC
- Rabbit
- human, mouse
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- 详细信息
- 技术资料
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
CoraLite® Plus 488 Fluorescent Dye
- 适应物种：
human, mouse
- 宿主：
Rabbit
- 应用范围：
IF/ICC
- 靶点：
Integrin alpha-5/CD49e
- 抗体英文名：
CoraLite® Plus 488-conjugated Integrin alpha-5/CD49e Recombinant monoclonal antibody
- 抗体名：
CoraLite® Plus 488-conjugated Integrin alpha-5/CD49e Recombinant monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF/ICC detected in | HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-84468-4 targets Integrin alpha-5/CD49e in IF/ICC applications and shows reactivity with human, mouse samples.
| 经测试应用 | IF/ICC |
| 经测试反应性 | human, mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| 别名 | Integrin Alpha-5, ITGA5, 241685A3, CD49 antigen-like family member E, CD49e |
| 计算分子量 | 115 kDa |
| 观测分子量 | 140 kDa |
| GenBank蛋白编号 | BC008786 |
| 基因名称 | Integrin alpha 5 |
| Gene ID (NCBI) | 3678 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P08648 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated alpha and beta subunits. Integrin alpha 5 (ITGA5), belongs to the integrin alpha chain family, primarily binds to Integrin beta 1 (ITGB1) to form an α5β1 heterodimer (PMID: 33711961). Integrin α5β1 is a specific receptor of fibronectin through its arginine-glycine-aspartic acid (RGD) binding site (PMID: 19608542). Integrin α5β1 plays roles in cell adhesion, migration and matrix formation, and has emerged as an essential mediator in many human carcinomas (PMID: 33408483).
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