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- 详细信息
- 技术资料
- 免疫原:
Recombinant human SLC25A22 protein
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
WB, Indirect ELISA
- 靶点:
SLC25A22
- 抗体英文名:
SLC25A22 Recombinant monoclonal antibody, PBS Only
- 抗体名:
SLC25A22 Recombinant monoclonal antibody, PBS Only
- 规格:
100ug
产品信息
86163-1-PBS targets SLC25A22 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag19958 Product name: Recombinant human SLC25A22 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 128-188 aa of BC023545 Sequence: KIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYK |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| 别名 | GC 1, GC1, GC-1, Glutamate/H(+) symporter 1, NET44 |
| 计算分子量 | 323 aa, 34 kDa |
| 观测分子量 | 30-34 kDa |
| GenBank蛋白编号 | BC023545 |
| 基因名称 | SLC25A22 |
| Gene ID (NCBI) | 79751 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9H936 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
SLC25A22 encodes a mitochondrial glutamate/H+ symporter with highly expression in brain, especially in astrocytes, where it controls glutamate uptake. The mutations of SLC25A22 are associated with the early/infantile epileptic encephalopathies. It has been shown that SLC25A22 plays a key role in promoting proliferation and migration in cancer, such as human colorectal cancer (CRC) and Gallbladder cancer (GBC). And there is a result that the expression of SLC25A22 in GBC was significantly higher than that in adjacent tissues. 25402-1-AP antibody is specific to SLC25A22.(PMID: 30814911, 25033742, 24596948)
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