Anti-Human LIGHT/CD258 Rabbit Recombinant Antibody, PBS Only  98063-1-PBS

Anti-Human LIGHT/CD258 Rabbit

Recombinant Antibody, PBS Only 98063-1-PBS
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  • ¥3600 - 5000
  • Proteintech已认证
  • 98063-1-PBS
  • 2025年10月09日
  • FC
  • Rabbit
  • human
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    • 详细信息
    • 技术资料
    • 亚型

      IgG

    • 保存条件

      Store at -80°C.

    • 克隆性

      Recombinant

    • 标记物

      Unconjugated

    • 适应物种

      human

    • 宿主

      Rabbit

    • 应用范围

      FC

    • 靶点

      LIGHT/CD258

    • 抗体英文名

      Anti-Human LIGHT/CD258 Rabbit Recombinant Antibody, PBS Only

    • 抗体名

      Anti-Human LIGHT/CD258 Rabbit Recombinant Antibody, PBS Only

    • 规格

      500ug/1mg

    规格:500ug产品价格:¥3600.0
    规格:1mg产品价格:¥5000.0
    Planning an IHC experiment? We recommend our IHCeasy TNFSF14/LIGHT Ready-To-Use IHC Kit. TNFSF14/LIGHT primary antibody included.

    产品信息

    98063-1-PBS targets LIGHT/CD258 in FC applications and shows reactivity with human samples.

    经测试应用 FC
    经测试反应性 human
    免疫原

    fusion protein

    宿主/亚型 Rabbit / IgG
    抗体类别 Recombinant
    产品类型 Antibody
    全称 tumor necrosis factor (ligand) superfamily, member 14
    别名 LIGHT, HVEM-L, HVEML, HVEM L, CD258
    计算分子量26KD
    GenBank蛋白编号NM_003807
    基因名称 LIGHT
    Gene ID (NCBI) 8740
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein A purfication
    UNIPROT IDO43557
    储存缓冲液 PBS only, pH 7.3.
    储存条件Store at -80°C.
    The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

    背景介绍

    LIGHT, also known as TNFSF14, HVEML, or CD258, is a type II transmembrane protein that belongs to the TNF superfamily (PMID: 9462508). It is predominantly expressed in lymphoid tissues and produced by activated T cells and immature dendritic cells (DCs) (PMID: 9462508; 10754304). Through its two primary functional receptors HVEM (TNFRSF14) and lymphotoxin β receptor (LTβR), LIGHT signaling is involved in development and maintenance of lymphoid tissues, as well as innate and adaptive immune responses (PMID: 24575096; 26720335). In addition to the membrane form, LIGHT can also exist as a soluble form generated by cleavage of the extracellular portion of the membrane form.

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