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Anti-Mouse CD107a / LAMP1 (1D4

B), PBS Only 65050-1-PBS
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  • ¥5800
  • Proteintech已认证
  • 65050-1-PBS
  • 2025年10月09日
  • IF/ICC, FC (Intra)
  • Rat
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG2a, kappa

    • 保存条件

      Store at -80°C.

    • 克隆性

      Monoclonal

    • 标记物

      Unconjugated

    • 适应物种

      mouse

    • 宿主

      Rat

    • 应用范围

      IF/ICC, FC (Intra)

    • 靶点

      CD107a / LAMP1

    • 抗体英文名

      Anti-Mouse CD107a / LAMP1 (1D4B), PBS Only

    • 抗体名

      Anti-Mouse CD107a / LAMP1 (1D4B), PBS Only

    • 规格

      100ug

    产品信息

    65050-1-PBS targets CD107a / LAMP1 in IF/ICC, FC (Intra) applications and shows reactivity with mouse samples.

    经测试应用 IF/ICC, FC (Intra)
    经测试反应性 mouse
    免疫原

    fusion protein

    宿主/亚型 Rat / IgG2a, kappa
    抗体类别 Monoclonal
    产品类型 Antibody
    全称 lysosomal-associated membrane protein 1
    别名 CD107a, Lamp1, 1D4B, Lamp 1
    GenBank蛋白编号BC006785
    基因名称 CD107a
    Gene ID (NCBI) 16783
    偶联类型 Unconjugated
    形式Liquid
    纯化方式Protein G purification
    UNIPROT IDP11438
    储存缓冲液 PBS only, pH 7.3.
    储存条件Store at -80°C.
    The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

    背景介绍

    LAMP1 (CD107a) is a heavily glycosylated membrane protein enriched in the lysosomal membrane. LAMP1 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP1 is expressed largely in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane (PMID: 16168398). Elevated LAMP1 expression at the cell surface has also been detected during platelet and granulocytic cell activation, as well as in some tumor cells (PMID: 29085473). LAMP1 functions to provide selectins with carbohydrate ligands. This protein has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis (PMID: 18835598; 29085473; 9426697).

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