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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG2a, kappa
- 保存条件:
Store at 2-8°C. Stable for one year after shipment.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
mouse
- 宿主:
Rat
- 应用范围:
FC
- 靶点:
CD71
- 抗体英文名:
Anti-Mouse CD71 (RI7217)
- 抗体名:
Anti-Mouse CD71 (RI7217)
- 规格:
100ug/500ug
| 规格: | 100ug | 产品价格: | ¥710.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥1930.0 |
经过测试的应用
| Positive FC detected in | C57BL/6 mouse bone marrow cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Flow Cytometry (FC) | FC : 0.5 ug per 10^6 cells in 100 μl suspension |
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65289-1-Ig targets CD71 in IF, FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 文献引用应用 | IF, FC |
| 经测试反应性 | mouse |
| 文献引用反应性 | human, mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG2a, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | transferrin receptor |
| 别名 | Tfrc, RI7217, TFR, TFR1, TR |
| GenBank蛋白编号 | BC054522 |
| 基因名称 | CD71 |
| Gene ID (NCBI) | 22042 |
| RRID | AB_3083747 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Affinity purification |
| UNIPROT ID | Q62351 |
| 储存缓冲液 | PBS with 0.09% sodium azide, pH 7.3. |
| 储存条件 | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule, creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.
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文献和实验| Species | Application | Title |
|---|---|---|
| mouse | FC | Cell Chem Biol Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptorAuthors - Ling-Yan Su |
| human | IF | Cancer Discov Functional reprogramming of neutrophils within the brain tumor microenvironment by hypoxia-driven histone lactylationAuthors - Alessio Ugolini |
(3 ). PKA is composed of two catalytic (C) and two regulatory (R) subunits and has type I and type II isozymes, with different R subunits, termed RI and RII, interacting with an identical C subunit (1 ). Thus far, four isoforms of R subunits, RIα, RIβ, RIIα
网络 二、Ig超家族的特点 (一)Ig超家族的结构特点 Ig超家族成员均含有1~7个Ig样结构域,每个Ig样结构域约含70~110个氨基酸残基。其二级结构是两个各含3~5个反平行β折叠股所形成的β片层(anti-parallel β-pleated sheet)平面,每个反平行β折叠股由5~10个氨基酸残基组成,β
网络 二、Ig超家族的特点 (一)Ig超家族的结构特点 Ig超家族成员均含有1~7个Ig样结构域,每个Ig样结构域约含70~110个氨基酸残基。其二级结构是两个各含3~5个反平行β折叠股所形成的β片层(anti-parallel β-pleated sheet)平面,每个反平行β折叠股由5~10个氨基酸残基组成,β
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