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- 详细信息
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
human
- 宿主:
Rabbit
- 应用范围:
WB, IHC, Indirect ELISA
- 靶点:
IGF2
- 抗体英文名:
IGF2 Recombinant monoclonal antibody, PBS Only
- 抗体名:
IGF2 Recombinant monoclonal antibody, PBS Only
- 规格:
100ug
产品信息
84643-1-PBS targets IGF2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IHC, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 | fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | insulin-like growth factor 2 (somatomedin A) |
| 别名 | 241746D3, IGF II, IGF-II, Insulin-like growth factor II Ala-25 Del, PP1446 |
| 观测分子量 | 20 kDa |
| 基因名称 | IGF2 |
| Gene ID (NCBI) | 3481 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P01344 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Insulin-like growth factor 2 (IGF2) is a crucial protein that plays a significant role in regulating growth, particularly during normal fetal development, and is also often dysregulated during tumorigenesis. IGF2 is one of the main ligands of the type 1 IGF receptor (IGF-1R), a tyrosine kinase receptor that transmits signals upon binding with IGF-II. IGF2 is predominantly secreted via the placenta during pregnancy and, after birth, primarily by hepatocytes, with its secretion being independent of growth hormone (GH) secretion, unlike IGF-I.
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