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- 详细信息
- 技术资料
- 免疫原:
Recombinant human FGL2 protein
- 亚型:
IgG2b
- 保存条件:
Store at -80°C.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, mouse
- 宿主:
Mouse
- 应用范围:
WB, IF-P, Indirect ELISA
- 靶点:
FGL2
- 抗体英文名:
FGL2 Monoclonal antibody, PBS Only
- 抗体名:
FGL2 Monoclonal antibody, PBS Only
- 规格:
100ug
产品信息
67152-1-PBS targets FGL2 in WB, IF-P, Indirect ELISA applications and shows reactivity with Human, mouse samples.
| 经测试应用 | WB, IF-P, Indirect ELISA |
| 经测试反应性 | Human, mouse |
| 免疫原 |
CatNo: Ag28619 Product name: Recombinant human FGL2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-148 aa of BC017813 Sequence: MKLANWYWLSSAVLAAYGFLVVANNETEEIKDERAKDVCPVRLESRGKCEEAGECPYQVSLPPLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKSCQDCKLQADDNGDPGRNGLLLPSTGAPGEVGDNRVRELESEVNKLSSELKFIF |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | fibrinogen-like 2 |
| 别名 | FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49 |
| 计算分子量 | 50 kDa |
| 观测分子量 | 70 kDa |
| GenBank蛋白编号 | BC017813 |
| 基因名称 | FGL2 |
| Gene ID (NCBI) | 10875 |
| RRID | AB_2882449 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q14314 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.
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