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- 详细信息
- 文献和实验
- 技术资料
- 服务名称:
大肠杆菌系统重组蛋白表达
- 提供商:
普健生物(武汉)科技有限公司
Uniprot号:P84244
基因名:H3-3a
蛋白名:Histone H3.3
蛋白别名:
Histone H3.3
服务内容:
| 服务项目 | 客户提供 | 服务内容 | 服务周期 | 交付内容 |
|---|---|---|---|---|
| 大肠杆菌系统 蛋白表达 |
基因序列 | 方案沟通 | 1天 | 方案报告 |
| 密码子优化和基因合成 | 5天 | 基因合成报告 | ||
| 表达纯化测试 | 3天 | 表达纯化测试报告 | ||
| 1L表达及纯化 | 3天 | 蛋白样品(3-5mg)及报告 | ||
| 放大发酵及纯化 | 7天 | 纯化的蛋白及报告 |
案例展示:

H3-3a相关研究文献:
1. Antisense oligonucleotide therapy for H3.3K27M diffuse midline glioma. [37043556]
2. A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation. [38066305]
3. Histone 3.3-related chromatinopathy: missense variants throughout H3-3A and H3-3B cause a range of functional consequences across species. [36867246]
4. Bryant-Li-Bhoj Neurodevelopmental Syndrome. [37782742]
5. De novo variants in H3-3A and H3-3B are associated with neurodevelopmental delay, dysmorphic features, and structural brain abnormalities. [34876591]
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文献和实验2. A new subtype of diffuse midline glioma, H3 K27 and BRAF/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation. [38066305]
3. Histone 3.3-related chromatinopathy: missense variants throughout H3-3A and H3-3B cause a range of functional consequences across species. [36867246]
4. Bryant-Li-Bhoj Neurodevelopmental Syndrome. [37782742]
5. De novo variants in H3-3A and H3-3B are associated with neurodevelopmental delay, dysmorphic features, and structural brain abnormalities. [34876591]
9.19 Nature:揭示组蛋白标记 H3K36me2 招募 DNMT3A 并影响基因间 DNA 甲基化
① Nature:揭示组蛋白标记 H3K36me2 招募 DNMT3A 并影响基因间 DNA 甲基化塔顿布朗拉赫曼综合征(Tatton–Brown–Rahman syndrome, TBRS)是一种儿童过度生长障碍,是由生殖系 DNMT3A 突变导致的。儿童期巨脑畸形综合征(Sotos syndrome)是由 NSD1 的单倍剂量不足引起的,其中 NSD1 是组蛋白甲基转移酶,催化组蛋白 H3 在 K36 位点发生二甲基化(H3K36me2)。在一项新的研究中,来自美国哥伦比亚大学欧文医学
Blastocyst embryo transfer into pseudopregnant recipient female mouse(图)
and exhibit bad planes of anesthesia when heavy. This is also a very inexpensive mouse to use. As an alternate, another strain I have used with considerable success is B6D2F1. These mice are hardy and display hybrid vigor. The Equipment For surgery
PROTOCOL General anesthesia inject i.p. 250µl/mouse of the ANESTHETIC mixture for verify the anesthetic effect check plantar reflexes (animal must be unresponsive to squeezing hind feet) Preparation
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