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- 详细信息
- 文献和实验
- 技术资料
- 服务名称:
大肠杆菌系统重组蛋白表达
- 提供商:
普健生物(武汉)科技有限公司
Uniprot号:Q3MHF7
基因名:MTAP
蛋白名:S-methyl-5'-thioadenosine phosphorylase
蛋白别名:
S-methyl-5'-thioadenosine phosphorylase, EC 2.4.2.28, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPase
服务内容:
| 服务项目 | 客户提供 | 服务内容 | 服务周期 | 交付内容 |
|---|---|---|---|---|
| 大肠杆菌系统 蛋白表达 |
基因序列 | 方案沟通 | 1天 | 方案报告 |
| 密码子优化和基因合成 | 5天 | 基因合成报告 | ||
| 表达纯化测试 | 3天 | 表达纯化测试报告 | ||
| 1L表达及纯化 | 3天 | 蛋白样品(3-5mg)及报告 | ||
| 放大发酵及纯化 | 7天 | 纯化的蛋白及报告 |
案例展示:

MTAP相关研究文献:
1. MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer. [37552839]
2. MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells. [26912360]
3. Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5. [26912361]
4. MTAP as an emerging biomarker in thoracic malignancies. [39357262]
5. MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage. [33450196]
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文献和实验2. MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells. [26912360]
3. Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5. [26912361]
4. MTAP as an emerging biomarker in thoracic malignancies. [39357262]
5. MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage. [33450196]
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