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- 湖北省武汉市
- Gallus gallus CISH重组蛋白表达
- 2025年09月11日
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- 详细信息
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- 服务名称：
大肠杆菌系统重组蛋白表达
Uniprot号：Q9PW70
基因名：CISH
蛋白名：Cytokine-inducible SH2-containing protein
蛋白别名：
Cytokine-inducible SH2-containing protein, CIS, CIS-1, Suppressor of cytokine signaling, SOCS
服务内容：
| 服务项目 | 客户提供 | 服务内容 | 服务周期 | 交付内容 |
|---|---|---|---|---|
| 大肠杆菌系统 蛋白表达 |
基因序列 | 方案沟通 | 1天 | 方案报告 |
| 密码子优化和基因合成 | 5天 | 基因合成报告 | ||
| 表达纯化测试 | 3天 | 表达纯化测试报告 | ||
| 1L表达及纯化 | 3天 | 蛋白样品(3-5mg)及报告 | ||
| 放大发酵及纯化 | 7天 | 纯化的蛋白及报告 |
案例展示：
CISH相关研究文献：
1. Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity. [32531207]
2. CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging. [37118554]
3. Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial. [40315882]
4. CISH is induced during DC development and regulates DC-mediated CTL activation. [22002016]
5. Cish knockout mice exhibit similar outcomes to malaria infection despite altered hematopoietic responses. [38029163]
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文献和实验2. CISH impairs lysosomal function in activated T cells resulting in mitochondrial DNA release and inflammaging. [37118554]
3. Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial. [40315882]
4. CISH is induced during DC development and regulates DC-mediated CTL activation. [22002016]
5. Cish knockout mice exhibit similar outcomes to malaria infection despite altered hematopoietic responses. [38029163]
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