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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
Secretory Phospholipase A2 Rabbit mAb
- 抗体英文名:
Secretory Phospholipase A2 Rabbit mAb
- 应用范围:
WB
- 宿主:
Recombinant Rabbit
- 适应物种:
Human;Mouse;Rat
- 抗原来源:
Recombinant Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 保存条件:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 亚型:
Rabbit IgG
- 免疫原:
A synthesized peptide derived from human PLA2G2A
purification
Affinity-chromatography
applications
WB
appl_detail
WB 1:1000-1:2000
other_names
MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
calculated_mw
14kDa
formulation
Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
uniprot
P14555
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文献和实验Purification and Assay of Mammalian Group I and Group IIa Secretory Phospholipase A2
Phospholipases A2 (PLA2 ) are a family of ubiquitous lipolytic enzymes that are found both as intracellular and secreted proteins. Secretory PLA2 s are small (14 kDa), homologous proteins that require millimolar Ca2+ for catalytic activity
The release of arachidonic acid (AA) from membrane phospholipids by phospholipase A2 (PLA2 ) is a critical step in the generation of lipid mediators by mast cells. AA released by PLA2 activity is metabolized to bioactive compounds
formation (2 ) and specific eicosanoids seem to be produced by specific cell types in response to various inflammatory stimuli (3 ). The multiple synthetic pathways suggest that multiple sites of inhibition may exist. Phospholipase A2 (PLA2 ) acts on cell
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