- ￥2000 - 3900
- Solarbio|ActivAb
- 北京
- K011076M
- 2025年08月22日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG1，κ
- 保存条件：
Store at 4℃ in dark.Do not freeze.
- 克隆性：
Monoclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Human
- 目录编号：
3672
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Mouse
- 应用范围：
FCM
- 浓度：
FCM 5uL/Test.
- 靶点：
CD49a
- 抗体英文名：
Anti-CD49a(PE) Monoclonal Antibody
- 抗体名：
CD 49a; CD49a; CD49 antigen-like family member A; CD49a; CD49a antigen; Integrin alpha-1; ITA1_HUMAN; Itga 1; ITGA1; Laminin and collagen receptor; Very late activation protein 1; VLA 1; VLA-1; VLA1
- 规格：
25T/100T
| 规格： | 25T | 产品价格： | ￥2000.0 |
|---|---|---|---|
| 规格： | 100T | 产品价格： | ￥3900.0 |
| 基本信息 | |
| 英文名称 | Anti-CD49a(PE) Monoclonal Antibody |
| 宿主 | Mouse |
| 克隆类型 | Monoclonal Antibody |
| 亚型 | IgG1，κ |
| 交叉反应 | Human |
| 应用 | FCM |
| 稀释比例 | FCM 5uL/Test. |
| 密度 | |
| 靶标 | CD49a |
| 别名 | CD 49a; CD49a; CD49 antigen-like family member A; CD49a; CD49a antigen; Integrin alpha-1; ITA1_HUMAN; Itga 1; ITGA1; Laminin and collagen receptor; Very late activation protein 1; VLA 1; VLA-1; VLA1 |
| 背景说明 | Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface，but，unlike most other cell surface receptors，they bind ligands with very low affinity. Due to their weak individual binding，integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Alpha 1 integrin along with alpha 2，alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin)，to form an alpha1 beta1 heterodimer，identified as the rat homologue to VLA1，which is involved in cellular adhesion to laminin and collagen. |
| Swiss Prot | P56199 |
| Gene ID | 3672 |
| 亚细胞定位 | Cell membrane |
| 储存条件 | Store at 4℃ in dark.Do not freeze. |
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Monoclonal Antibody-Based Strategies in Autoimmunity and Transplantation
of therapeutic monoclonal antibodies in the fields of transplantation and autoimmunity, and discuss the salient features of antibodies presently used in the clinic-notably anti-T-cell and anticytokine antibodies. The discussion will also focus on the unique
4-Hydroxy-2-Nonenal (4-HNE) Staining by Anti-HNE Antibody
using an anti-4-HNE monoclonal antibody (MAb) (6 –8 ) and labeled goat anti-mouse IgG antibody (9 ).
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