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- 2025年08月22日
- WB
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide of human HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 适应物种：
Mouse
- 抗原来源：
A synthetic peptide of human HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1
- 目录编号：
3123/3127/3126/3115
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
WB 1:1000-3000.
- 靶点：
HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1
- 抗体英文名：
Anti-HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1 Polyclonal Antibody
- 抗体名：
HLA类组织相容性抗原，DRB1/DRB5/DRB4/DPB1链
- 规格：
20ul/100ul/50ul
| 规格： | 20ul | 产品价格： | ￥480.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
| 规格： | 50ul | 产品价格： | ￥960.0 |
| 基本信息 | |
| 英文名称 | Anti-HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1 Polyclonal Antibody |
| 中文名称 | HLA类组织相容性抗原，DRB1/DRB5/DRB4/DPB1链 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse |
| 预测交叉反应 | Human(100%);Cow(87.5%) |
| 应用 | WB |
| 稀释比例 | WB 1:1000-3000. |
| 密度 | |
| 靶标 | HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1 |
| 别名 | HLA-DRB1-2B1F_HUMAN; DR1; DR16; DR5; DR8; DRB1; DRw10; DW2.2/DR2.2; FLJ75017; FLJ76359; HLA class II antigen beta chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA-DR-beta 1; HLA-DR1B; HLA-DRB; HLA-DRB1; human leucocyte antigen DRB1; Leucocyte antigen DR beta 1 chain; leucocyte antigen DRB1; lymphocyte antigen DRB1; major histocompatibility complex, class II, DR beta 1; MHC class II antigen; MHC class II antigen DRB1*15; MHC class II antigen HLA-DR13; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; SS1; HLA-DRB3; HLA-DRB5-HLA class II histocompatibility antigen, DR beta 5 chain;DR beta-5;DR2-beta-2;Dw2;MHC class II antigen DRB5;HLA-DRB5;HLA-DRB4-HLA class II histocompatibility antigen, DR beta 4 chain;MHC class II antigen DRB4;HLA-DRB4; HLA-DPB1-HLA class II histocompatibility antigen, DP beta 1 chain;HLA class II histocompatibility antigen, DP(W4) beta chain;C class II antigen DPB1;HLA-DPB1; |
| 背景说明 | HLA-DRB1-HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB); both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3; DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3; DRB4 and DRB5. There are 4 related pseudogenes: DRB2; DRB6; DRB7; DRB8 and DRB9. [provided by RefSeq; Jul 2008] |
| Swiss Prot | P01911/Q30154/P13762/P04440 |
| Gene ID | 3123/3127/3126/3115 |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | A synthetic peptide of human HLA-DRB1/HLA-DRB5/HLA-DRB4/HLA-DPB1 |
| Public Immunogen Range | 50-100/266aa |
| 理论分子量 | 29/30kDa |
| 实际分子量 | 35kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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Preparation and Characterization of Anti-phage Serum
This chapter describes a method for the generation of polyclonal antibodies against bacteriophages and how these may be assayed immunochemically and biologically.
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