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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide of human TPSAB1/TPSB2
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Mouse;Rat
- 抗原来源:
A synthetic peptide of human TPSAB1/TPSB2
- 目录编号:
7177/64499
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 浓度:
WB 1:500-2000.
- 靶点:
TPSAB1/TPSB2
- 抗体英文名:
Anti-TPSAB1/TPSB2 Polyclonal Antibody
- 抗体名:
类胰蛋白酶α/β-1/2
- 规格:
20ul/100ul/50ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 基本信息 | |
| 英文名称 | Anti-TPSAB1/TPSB2 Polyclonal Antibody |
| 中文名称 | 类胰蛋白酶α/β-1/2 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat |
| 预测交叉反应 | Dog(100%);Pig(93.8%);Sheep(87.5%);Hamster(93.8%) |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 密度 | |
| 靶标 | TPSAB1/TPSB2 |
| 别名 | alpha II; Lung tryptase; Mast cell alpha II tryptase; Mast cell beta I tryptase; Mast cell protease 7; Mast cell protease II; MCP 7; Pituitary tryptase; Skin tryptase; TPS 1; TPS1; TPS2; TPSAB1; TPSAB1 protein; TPSB1; Tryptase 1; Tryptase alpha 1; tryptase alpha I included; Tryptase alpha II; tryptase alpha II included; tryptase alpha included; tryptase alpha/beta 1; Tryptase beta 1; tryptase beta I included; Tryptase I; tryptase I included; Tryptase III; Tryptase skin; |
| 背景说明 | TPSB1-Tryptases comprise a family of trypsin-like serine proteases; the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers; and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon; which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation; such that the alleles were once thought to represent two separate genes; alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils; alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorder ;TPSB2-Tryptases comprise a family of trypsin-like serine proteases; the peptidase family S1. ;TPSB2-Tryptases are enzymatically active only as heparin-stabilized tetramers; and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon; which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation; such that the alleles were once thought to represent two separate genes; beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils; alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq; Jul 2008] |
| Swiss Prot | Q15661/P20231 |
| Gene ID | 7177/64499 |
| 亚细胞定位 | Secreted |
| 免疫原 | A synthetic peptide of human TPSAB1/TPSB2 |
| Public Immunogen Range | 225-275/275aa |
| 理论分子量 | 30/31kDa |
| 实际分子量 | 30kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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