K114880P Anti-PRKAR2B Polyclonal Antibody

K114880P Anti-PRKAR2B Polyclon

al Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K114880P
  • 2025年08月22日
  • IHC
  • Rabbit
  • Human;Mouse;Rat
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant protein of human PRKAR2B

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Mouse;Rat

    • 抗原来源

      Recombinant protein of human PRKAR2B

    • 目录编号

      5577

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC

    • 浓度

      IHC 1:50-200.

    • 靶点

      PRKAR2B

    • 抗体英文名

      Anti-PRKAR2B Polyclonal Antibody

    • 抗体名

      cAMP调节依赖性蛋白激酶II型β

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-PRKAR2B Polyclonal Antibody
    中文名称cAMP调节依赖性蛋白激酶II型β
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Mouse;Rat
    预测交叉反应Bovine
    应用IHC
    稀释比例IHC 1:50-200.
    密度
    靶标PRKAR2B
    别名AI451071;AW061005;cAMP dependent protein kinase type II beta regulatory chain;cAMP dependent protein kinase type II beta regulatory subunit;cAMP-dependent protein kinase type II-beta regulatory subunit;H RG363E19.2;KAP3_HUMAN;MGC116401;Pkarb2;PRKAR 2;PRKAR2;PRKAR2B;Protein kinase cAMP dependent regulatory type II beta;RATDNA;RII beta;RII(beta);RIIbeta;WUGSC:H RG363E19.2;
    背景说明cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008]
    Swiss ProtP31323
    Gene ID5577
    亚细胞定位Cytoplasm
    免疫原Recombinant protein of human PRKAR2B
    Public Immunogen Range1-350aa
    理论分子量46kDa
    EC
    纯化方法Octanoic acid-ammonium sulfate precipitation
    储存液PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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