K109510P Anti-NR0B2 Polyclonal

Antibody

14 年钻石会员

免疫原：
Recombinant protein of human NR0B2
亚型：
IgG
保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
克隆性：
Polyclonal Antibody
标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
适应物种：
Rat;Mouse
抗原来源：
Recombinant protein of human NR0B2
目录编号：
8431
级别：
实验级别
库存：
现询
供应商：
北京索莱宝科技有限公司
宿主：
Rabbit
应用范围：
WB
浓度：
WB 1:1000-3000.
靶点：
NR0B2
抗体英文名：
Anti-NR0B2 Polyclonal Antibody
抗体名：
核受体亚家族0,B组成员2抗体
规格：
20ul/100ul/50ul

基本信息
英文名称	Anti-NR0B2 Polyclonal Antibody
中文名称	核受体亚家族0,B组成员2抗体
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
交叉反应	Rat;Mouse
应用	WB
稀释比例	WB 1:1000-3000.
密度
靶标	NR0B2
背景说明	Transcriptional regulator that acts as a negative regulator of receptor-dependent signaling pathways (By similarity). Specifically inhibits transactivation of the nuclear receptor with which it interacts (By similarity). Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated transcription complex for NEUROD1 (PubMed:14752053). Essential component of the liver circadian clock which via its interaction with NR1D1 and RORG regulates NPAS2-mediated hepatic lipid metabolism (By similarity). Regulates the circadian expression of cytochrome P450 (CYP) enzymes (By similarity). Represses: NR5A2 and HNF4A to down-regulate CYP2C38, NFLI3 to up-regulate CYP2A5, BHLHE41/HNF1A axis to up-regulate CYP1A2, CYP2E1 and CYP3A11, and NR1D1 to up-regulate CYP2B10, CYP4A10 and CYP4A14 (By similarity).
Swiss Prot	Q15466
Gene ID	8431
亚细胞定位	Nucleus Cytoplasm
免疫原	Recombinant protein of human NR0B2
Public Immunogen Range	1-257aa
理论分子量	29kDa
EC
纯化方法	Affinity purification
储存液	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件	Store at -20℃. Avoid freeze/thaw cycles.

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