K109384P Anti-NME2 Polyclonal

Antibody

14 年钻石会员

免疫原：
A synthetic peptide of human NME2
亚型：
IgG
保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
克隆性：
Polyclonal Antibody
标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
适应物种：
Mouse;Rat;Human
抗原来源：
A synthetic peptide of human NME2
目录编号：
4831/654364
级别：
实验级别
库存：
现询
供应商：
北京索莱宝科技有限公司
宿主：
Rabbit
应用范围：
IHC
浓度：
IHC 1:25-100.
靶点：
NME2
抗体英文名：
Anti-NME2 Polyclonal Antibody
抗体名：
肿瘤抑制基因NME2抗体
规格：
20ul/100ul/50ul

基本信息
英文名称	Anti-NME2 Polyclonal Antibody
中文名称	肿瘤抑制基因NME2抗体
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
交叉反应	Mouse;Rat;Human
预测交叉反应	Cow(93.3%);Chicken(86.7%);Dog(100%);Pig(100%);Chimpanzee(100%)
应用	IHC
稀释比例	IHC 1:25-100.
密度
靶标	NME2
背景说明	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically. Binds to both single-stranded guanine- and cytosine-rich strands within the nuclease hypersensitive element (NHE) III1 region of the MYC gene promoter. Does not bind to duplex NHE III1. Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity. Binds both folded and unfolded G4 with similar low nanomolar affinities. Stabilizes folded G4s regardless of whether they are prefolded or not. Exhibits histidine protein kinase activity.
Swiss Prot	P22392
Gene ID	4831/654364
亚细胞定位	Cytoplasm Nucleus
免疫原	A synthetic peptide of human NME2
Public Immunogen Range	95-145/152aa
理论分子量	17/30kDa
EC
纯化方法	Affinity purification
储存液	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件	Store at -20℃. Avoid freeze/thaw cycles.

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