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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide of human SARS glycoprotein S1
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 抗原来源:
A synthetic peptide of human SARS glycoprotein S1
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA;IF;ICC;IHC
- 浓度:
ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:100-500.
- 靶点:
SARS glycoprotein S1
- 抗体英文名:
Anti-SARS spike glycoprotein S1 Polyclonal Antibody
- 抗体名:
SARS病毒S2蛋白抗体
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥2100.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥3500.0 |
| 基本信息 | |
| 英文名称 | Anti-SARS spike glycoprotein S1 Polyclonal Antibody |
| 中文名称 | SARS病毒S2蛋白抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 预测交叉反应 | SARS-CoV |
| 应用 | ELISA;IF;ICC;IHC |
| 稀释比例 | ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:100-500. |
| 密度 | |
| 靶标 | SARS glycoprotein S1 |
| 别名 | E2;E2 glycoprotein;Human coronavirus spike glycoprotein;Peplomer protein;S;S glycoprotein;SPIKE_CVHSA;Severe acute respiratory syndrome spike glycoprotein;Severe acute respiratory syndrome virus spike glycoprotein;Spike glycoprotein;VGL2. SARS-CoV |
| 背景说明 | S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. |
| Swiss Prot | P59594 |
| 免疫原 | A synthetic peptide of human SARS glycoprotein S1 |
| Public Immunogen Range | 101-200/1255aa |
| 理论分子量 | 138kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA,0.03% Proclin300 and 50% Glycerol. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验全球首次!分离的新冠病毒中和抗体,还可同时抗 SARS 病毒
抗原表位,为预防和治疗新型冠状病毒肺炎 COVID- 19 提供了可能。图片来源:bioRxiv通常,冠状病毒中和抗体主要靶向介导进入宿主细胞的病毒表面三聚体刺突糖蛋白(Spike Glycoproteins,S 蛋白)。S 蛋白具有介导细胞附着的两个功能亚基:负责受体识别的 S1 亚基(存在四个核心结构域 S1 A/B/C/D)以及促使病毒与细胞膜融合的 S2 亚基。强大的中和抗体通常会靶向 S1 中的受体相互作用位点,从而使受体相互作用失效。之前的研究表明,SARS-CoV- 2 和 SARS-CoV
of the tryptic peptides derived from the purified enzyme revealed two amino acid sequences homologous to the 14-3-3 proteins. A polyclonal antibody was raised against purified ST-IV. A 33 kDa protein was co-immunoprecipitated from rat brain extracts with the anti
-Whittaker Europe, Verviers, Belgium) supplemented exactly as described previously [10]. B cell activation was performed using varying concentrations of a polyclonal B cell activator, i.e. anti-µ-Fab'2 fragments (Irvine Scientific, Santa Anna, CA, USA
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