Anti-CD52 Reference Antibody(A

Measuring Humanized Antibodies in Plasma of Patients Treated With Antibody-Based Therapy Using Bead-Based Flow Cytometry: The Story of Alemtuzumab

Alemtuzumab (Campath), the humanized rat monoclonal antibody that targets the CD52 surface antigen, is currently used for treatment of patients with resistant chronic lymphocytic leukemia. Monitoring levels of the antibody in plasma/serum

Isolation of Anti-Hapten Specific Antibody Fragments from Combinatorial Libraries

system unless presented as an epitope conjugated to a suitable immunogenic carrier protein, such as bovine thyroglobulin. The principal interest in anti-hapten Abs is as detection molecules for use in diagnostic assays. These typically use dipstick (qualitative

Assays for Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) and Reverse ADCC (Redirected Cytotoxicity) in Human Natural Killer Cells

immunecomplexed IgG and therefore target cells that, not recognized spontaneously by NK cells, are sensitized with anti-target cell antibodies (Abs) of the IgG class. The two types of cytotoxicity elicited are referred to as “spontaneous” and “Ab-dependent’ cell