In Vivo Shuttle LNP-Lung

In Vitro Shuttle Mutagenesis Using Engineered Mariner Transposons

. This can be performed directly in vivo, but often it is more convenient to generate transpositions in vitro for subsequent analysis in vivo, in a process termed “shuttle mutagenesis.” The Drosophila element mariner is well suited for application by either route. Minimal

Chemoprevention of Lung Cancer

“Hypothesis-driven chemoprevention of lung cancer, when put to the test of randomized large-scale clinical trials, so far has been disappointing, unlike important successes with selective estrogen receptors modulators for breast cancer

Xenogeneic Lung Transplantation Models

and two different experimental models, the ex vivo porcine-to-human lung perfusion and the in vivo xenogeneic lung transplantation, are presented. We focus on the technical details of these lung xenograft models in sufficient detail, list the needed materials