K110536P Anti-DDX1 Polyclonal Antibody

K110536P Anti-DDX1 Polyclonal

Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K110536P
  • 2025年08月20日
  • WB;IHC
  • Rabbit
  • Human;Rat;Mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant protein of human DDX1

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze/thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Rat;Mouse

    • 抗原来源

      Recombinant protein of human DDX1

    • 目录编号

      1653

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      WB;IHC

    • 浓度

      WB 1:1000-3000. IHC 1:50-200.

    • 靶点

      DDX1

    • 抗体英文名

      Anti-DDX1 Polyclonal Antibody

    • 抗体名

      DEAD盒多肽1抗体

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-DDX1 Polyclonal Antibody
    中文名称DEAD盒多肽1抗体
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Rat;Mouse
    应用WB;IHC
    稀释比例WB 1:1000-3000. IHC 1:50-200.
    密度
    靶标DDX1
    别名ATP dependent helicase DDX1, ATP-dependent helicase DDX1, ATP-dependent RNA helicase DDX1, DBP RB, DBP-RB, DDX1, DDX1_HUMAN, DEAD (Asp Glu Ala Asp) box polypeptide 1, DEAD box 1, DEAD box polypeptide 1, DEAD box protein 1, DEAD box protein retinoblastoma, DEAD-box protein 1, DEAD-box protein-retinoblastoma, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 1
    背景说明Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation. Acts as a positive transcriptional regulator of cyclin CCND2 expression. Binds to the cyclin CCND2 promoter region. Associates with chromatin at the NF-kappa-B promoter region via association with RELA. Binds to poly(A) RNA. May be involved in 3'-end cleavage and polyadenylation of pre-mRNAs. Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB: together with archease (ZBTB8OS), acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1. Specifically binds (via helicase ATP-binding domain) on both short and long poly(I:C) dsRNA.
    Swiss ProtQ92499
    Gene ID1653
    亚细胞定位Cytoplasm Nucleus
    免疫原Recombinant protein of human DDX1
    Public Immunogen Range391-740aa
    理论分子量70/82kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze/thaw cycles.

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