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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein of human ATP2A2
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Rat;Mouse
- 抗原来源:
Recombinant protein of human ATP2A2
- 目录编号:
488
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB;IHC
- 浓度:
WB 1:1000-3000. IHC 1:50-200.
- 靶点:
ATP2A2
- 抗体英文名:
Anti-ATP2A2 Polyclonal Antibody
- 抗体名:
钙离子转运ATP酶A2抗体
- 规格:
20ul/100ul/50ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 基本信息 | |
| 英文名称 | Anti-ATP2A2 Polyclonal Antibody |
| 中文名称 | 钙离子转运ATP酶A2抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Rat;Mouse |
| 应用 | WB;IHC |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| 密度 | |
| 靶标 | ATP2A2 |
| 别名 | ATP dependent calcium pumpsc, ATP2A2, ATP2B, ATPase Ca++ transporting cardiac muscle slow twitch 2, Ca++ transporting cardiac muscle slow twitch 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type slow twitch skeletal muscle isoform, DAR, Darier disease, DD, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Sarcoplasmic or endoplasmic reticulum calcium ATP, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA 2, SERCA2, SR Ca(2+)-ATPase 2, AT2A2_HUMAN |
| 背景说明 | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle (PubMed:16402920). Acts as a regulator of TNFSF11-mediated Ca2+ signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca (2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca (2+) signaling cascades that promote osteoclast differentiation and activation (By similarity). |
| Swiss Prot | P16615 |
| Gene ID | 488 |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human ATP2A2 |
| Public Immunogen Range | 483-700aa |
| 理论分子量 | 110/112/115kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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K110557P Anti-ATP2A2 Polyclonal Antibody
¥480 - 1600







