K110681P Anti-APH1A Polyclonal Antibody

K110681P Anti-APH1A Polyclonal

Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K110681P
  • 2025年08月20日
  • IHC
  • Rabbit
  • Human;Mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human APH1A

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze/thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Mouse

    • 抗原来源

      A synthetic peptide of human APH1A

    • 目录编号

      51107

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      IHC

    • 浓度

      IHC 1:50-200.

    • 靶点

      APH1A

    • 抗体英文名

      Anti-APH1A Polyclonal Antibody

    • 抗体名

      早老素γ分泌酶抗体

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-APH1A Polyclonal Antibody
    中文名称早老素γ分泌酶抗体
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Mouse
    应用IHC
    稀释比例IHC 1:50-200.
    密度
    靶标APH1A
    别名Anterior Pharynx Defective 1, Anterior pharynx defective 1 homolog A, APH 1A, Aph 1alpha, APH-1a, Aph-1alpha, Aph1a, APH1A_HUMAN, CGI 78, CGI78, Gamma secretase subunit APH 1A, Gamma Secretase Subunit APH1a, Gamma-secretase subunit APH-1A, Likely ortholog of C. elegans anterior pharynx defective 1A, Presenilin Stabilization Factor, Presenilin-stabilization factor, PSF, UNQ579/PRO1141
    背景说明This gene encodes a component of the gamma secretase complex that cleaves integral membrane proteins such as Notch receptors and beta-amyloid precursor protein. The gamma secretase complex contains this gene product, or the paralogous anterior pharynx defective 1 homolog B (APH1B), along with the presenilin, nicastrin, and presenilin enhancer-2 proteins. The precise function of this seven-transmembrane-domain protein is unknown though it is suspected of facilitating the association of nicastrin and presenilin in the gamma secretase complex as well as interacting with substrates of the gamma secretase complex prior to their proteolytic processing. Polymorphisms in a promoter region of this gene have been associated with an increased risk for developing sporadic Alzheimer's disease. Alternative splicing results in multiple protein-coding and non-protein-coding transcript variants.
    Swiss ProtQ96BI3
    Gene ID51107
    亚细胞定位Cytoplasm
    免疫原A synthetic peptide of human APH1A
    Public Immunogen Range215-265/265aa
    理论分子量21/27/29kDa
    EC
    纯化方法Octanoic acid-ammonium sulfate precipitation
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze/thaw cycles.

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