K109027P Anti-PPIF Polyclonal

Antibody

14 年钻石会员

免疫原：
Recombinant protein of human PPIF
亚型：
IgG
保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
克隆性：
Polyclonal Antibody
标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
适应物种：
Human;Mouse
抗原来源：
Recombinant protein of human PPIF
目录编号：
10105
级别：
实验级别
库存：
现询
供应商：
北京索莱宝科技有限公司
宿主：
Rabbit
应用范围：
WB;IHC
浓度：
WB 1:1000-3000. IHC 1:100-300.
靶点：
PPIF
抗体英文名：
Anti-PPIF Polyclonal Antibody
抗体名：
肽酰脯氨酰异构酶F抗体
规格：
20ul/100ul/50ul

基本信息
英文名称	Anti-PPIF Polyclonal Antibody
中文名称	肽酰脯氨酰异构酶F抗体
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
交叉反应	Human;Rat;Mouse
应用	WB;IHC
稀释比例	WB 1:1000-3000. IHC 1:100-300.
密度
靶标	PPIF
别名	CYP3;CyP-M;Cyp-D;CypD
背景说明	PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.
Swiss Prot	P30405
Gene ID	10105
亚细胞定位	Cytoplasm
免疫原	Recombinant protein of human PPIF
Public Immunogen Range	1-207aa
理论分子量	16/22kDa
EC
纯化方法	Affinity purification
储存液	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
储存条件	Store at -20℃. Avoid freeze/thaw cycles.

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