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- 详细信息
- 技术资料
- 抗体名:
Alexa Fluor® 488 anti-mouse Ly-6A/E (Sca-1)
- 抗体英文名:
Alexa Fluor® 488 anti-mouse Ly-6A/E (Sca-1)
- 供应商:
上海善然生物科技有限公司
- 保存条件:
2-8℃
- 规格:
100ug
Alexa Fluor® 488 anti-mouse Ly-6A/E (Sca-1) Antibody
D7
Catalog# / Size
108116 / 100 µg
Clone
Regulatory Status RUO
Other Names Sca-1
Isotype Rat IgG2a, κ
Description Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a
glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In
mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and
129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T
lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1,
and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of
Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype
mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
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