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- 详细信息
- 技术资料
- 免疫原:
Recombinant protein of human PELI1
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Mouse
- 抗原来源:
Recombinant protein of human PELI1
- 目录编号:
57162
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA;IHC
- 浓度:
IHC 1:50-200. ELISA 1:3000-30000.
- 靶点:
PELI1
- 抗体英文名:
Anti-PELI1 Polyclonal Antibody
- 抗体名:
E3泛素蛋白连接酶pellino同源物1抗体
- 规格:
20ul/100ul/50ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 基本信息 | |
| 英文名称 | Anti-PELI1 Polyclonal Antibody |
| 中文名称 | E3泛素蛋白连接酶pellino同源物1抗体 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse |
| 应用 | ELISA;IHC |
| 稀释比例 | IHC 1:50-200. ELISA 1:3000-30000. |
| 密度 | |
| 靶标 | PELI1 |
| 别名 | PELI1,PRISM,E3 ubiquitin-protein ligase pellino homolog 1,Pellino-1,EC 2.3.2.27,Pellino-related intracellular-signaling molecule,RING-type E3 ubiquitin transferase pellino homolog 1 |
| 背景说明 | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation (PubMed:12496252, PubMed:17675297). Mediates 'Lys-48'-linked polyubiquitination of RIPK3 leading to its subsequent proteasome-dependent degradation; preferentially recognizes and mediates the degradation of the 'Thr-182' phosphorylated form of RIPK3 (PubMed:29883609). Negatively regulates necroptosis by reducing RIPK3 expression (PubMed:29883609). Mediates 'Lys-63'-linked ubiquitination of RIPK1 (PubMed:29883609). |
| Swiss Prot | Q96FA3 |
| Gene ID | 57162 |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | Recombinant protein of human PELI1 |
| Public Immunogen Range | 1-350aa |
| 理论分子量 | 46kDa |
| EC | |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 储存液 | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
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K111011P Anti-PELI1 Polyclonal Antibody
¥480 - 1600







