K112829P Anti-INPP5D Polyclonal Antibody

K112829P Anti-INPP5D Polyclona

l Antibody
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  • ¥480 - 1600
  • Solarbio|ActivAb
  • 北京
  • K112829P
  • 2025年08月13日
  • WB;IHC
  • Rabbit
  • Human;Mouse
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    • 详细信息
    • 技术资料
    • 免疫原

      A synthetic peptide of human INPP5D

    • 亚型

      IgG

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 克隆性

      Polyclonal Antibody

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750

    • 适应物种

      Human;Mouse

    • 抗原来源

      A synthetic peptide of human INPP5D

    • 目录编号

      3635

    • 级别

      实验级别

    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 应用范围

      WB;IHC

    • 浓度

      WB 1:2000-5000. IHC 1:25-100.

    • 靶点

      INPP5D

    • 抗体英文名

      Anti-INPP5D Polyclonal Antibody

    • 抗体名

      SH2结构含磷酸肌醇SHIP1抗体

    • 规格

      20ul/100ul/50ul

    规格:20ul产品价格:¥480.0
    规格:100ul产品价格:¥1600.0
    规格:50ul产品价格:¥960.0
    基本信息
    英文名称Anti-INPP5D Polyclonal Antibody
    中文名称SH2结构含磷酸肌醇SHIP1抗体
    宿主Rabbit
    克隆类型Polyclonal Antibody
    亚型IgG
    交叉反应Human;Mouse
    应用WB;IHC
    稀释比例WB 1:2000-5000. IHC 1:25-100.
    密度
    靶标INPP5D
    别名Inositol polyphosphate 5 phosphatase of 145kDa; 4; 5-trisphosphate 5-phosphatase 1; hp51CN; Inositol polyphosphate 5 phosphatase 145kDa; Inositol polyphosphate 5 phosphatase; Inositol polyphosphate-5-phosphatase of 145 kDa; INPP5D; MGC104855; MGC142140; MGC142142; p150Ship; Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 1; Phosphatidylinositol-3; SH2 containing inositol phosphatase isoform b; SH2 domain containing inositol 5' phosphatase 1;
    背景说明This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
    Swiss ProtQ92835
    Gene ID3635
    亚细胞定位Cell membrane Cytoplasm
    免疫原A synthetic peptide of human INPP5D
    Public Immunogen Range1005-1055/1189aa
    理论分子量109/133kDa
    实际分子量140kDa
    EC
    纯化方法Affinity purification
    储存液PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3.
    储存条件Store at -20℃. Avoid freeze / thaw cycles.

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