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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant protein of human UBL4A
- 亚型:
IgG
- 保存条件:
Store at -20℃. Avoid freeze / thaw cycles.
- 克隆性:
Polyclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human;Mouse;Rat
- 抗原来源:
Recombinant protein of human UBL4A
- 目录编号:
8266
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 应用范围:
IHC
- 浓度:
IHC 1:25-100.
- 靶点:
UBL4A
- 抗体英文名:
Anti-UBL4A Polyclonal Antibody
- 抗体名:
DX254E;DXS254E;G6PD;GDX;OTTHUMP00000061462;Ubiquitin like 4;Ubiquitin like 4A;Ubiquitin like protein 4A;Ubiquitin like protein GDX;Ubiquitin-like protein 4A;Ubiquitin-like protein GDX;UBL 4;UBL 4A;UBL4;Ubl4a;UBL4A_HUMAN;
- 规格:
20ul/100ul/50ul
| 规格: | 20ul | 产品价格: | ¥480.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1600.0 |
| 规格: | 50ul | 产品价格: | ¥960.0 |
| 基本信息 | |
| 英文名称 | Anti-UBL4A Polyclonal Antibody |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human;Mouse;Rat |
| 预测交叉反应 | Zebrafish;Sablefish;Rabbit;Horse;Monkey;Gorilla |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 密度 | |
| 靶标 | UBL4A |
| 别名 | DX254E;DXS254E;G6PD;GDX;OTTHUMP00000061462;Ubiquitin like 4;Ubiquitin like 4A;Ubiquitin like protein 4A;Ubiquitin like protein GDX;Ubiquitin-like protein 4A;Ubiquitin-like protein GDX;UBL 4;UBL 4A;UBL4;Ubl4a;UBL4A_HUMAN; |
| 背景说明 | As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD, a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome. |
| Swiss Prot | P11441 |
| Gene ID | 8266 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human UBL4A |
| Public Immunogen Range | 1-158aa |
| 理论分子量 | 18kDa |
| EC | |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇:make an Antibody against a Peptides 下一篇:Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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